USMLE Internal Medicine Review 10 12 Myxedema Lab Clues, Findings

USMLE Internal Medicine Review 10 12 Myxedema Lab Clues, Findings

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Play USMLE Audio MP3 10 12 Myxedema Lab Clues, Findingss Below

 

Begin 10 12 Myxedema Lab Clues, Findings Transcription

Lab clues as to the diagnosis of myxedema coma include four telling indicators. First another word for milky appearing serum. Starts with an L. Lactescent serum.

Second, high serum content of which class of yellow-red pigments or lipochromes containing precursors of the A vitamins?

  • High serum keratin.

Third, elevated serum content of the most abundant steroid in animal tissues, especially in bile and gall stones. Elevated serum cholesterol.

And fourth, increased protein level in which bodily fluid other than the blood?

  • Increased cerebrospinal fluid protein.

And which three types of effusions with high protein content may be present in the myxedema coma patient? Just list them please.

  • Pleural, pericardial, or abdominal effusions with high protein content may be present in the myxedema coma patients.

What is an effusion in simple terms?

  • An effusion is the escape of fluid from the blood vessels or lymphatics into surrounding tissue or cavity.

Student doctor please pause the tape and summarize lab clues as to the diagnosis of myxedema coma. Please include four telling indicators and three types of effusions with high protein content which may be present.

Lab clues as to the diagnosis of myxedema coma include lactescent serum, high serum keratin and cholesterol, and increased cerebrospinal fluid protein. Pleural, pericardial, or abdominal effusions with high protein content may also be present.

Serum test of the myxedema coma patient reveal a low free Thyroxine or free Thyroxine index and a markedly elevated TSH is thyroidal radioactive iodine uptake high or low?

  • Low;

And are thyroid auto-antibodies usually positive or negative with myxedema coma patient?

  • Strongly positive, often indicating underlying chronic thyroiditis.

What are two likely ECG findings with the myxedema coma patient?

  • ECG of a myxedema coma patient likely shows sinus bradycardia and low voltage.

If lab studies are not readily available upon what will diagnosis of myxedema coma depend?

  • In the absence of reliable lab studies, diagnosis of myxedema coma must be made clinically.

Student doctor please pause the tape and summarize the following areas in the diagnosis of myxedema coma, free Thyroxine and TSH, thyroidal radioactive iodine uptake, thyroid auto-antibodies, and ECG findings.

  • Serum test of a myxedema coma patient reveal a low free Thyroxine or free Thyroxine index and a markedly elevated TSH. Thyroidal radioactive iodine uptake is low and thyroidal auto-antibodies are usually strongly positive, often indicating underlying chronic thyroiditis. Likely ECG findings include sinus bradycardia and low voltage. If lab studies are not readily available, diagnosis must be made clinically.

****END OF TRANSCRIPTION****

 

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