USMLE Step 1 Renal Physiology 1 Review 58 03 Additional Functions

USMLE Step 1 Renal Physiology 1 Review 58 03 Additional Functions

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Play USMLE Audio MP3 58 03 Additional Functions Below

Begin 58 03 Additional Functions Transcription

The kidneys have several other functions besides the maintenance of homeostasis. One of these additional functions starts with HP.  What is it?

  • Hormone production.

What enzyme produced by the kidneys helps them regulate blood pressure? It starts with an R.

  • The kidneys produce the enzyme renin which helps regulate blood pressure.

What hormone produced by the kidneys regulates the production of red blood cells in bone marrow? Its acronym is REF.

  • Renal erythropoietic factor.

What two vasoactive substances are also produced by the kidneys? They start with K and P.

  • Kinins and prostglandins.

What is another function of the kidneys having to do with a vitamin?

  • Activation of vitamin D3 is another function of the kidneys.

This last one is a function that the kidneys serve when the body is in dire straits such as with prolonged starvation. Name one other condition that would activate the kidney’s production and secretion of glucose from non-carbohydrate sources. It starts with CRA.

  • Chronic respiratory acidosis.

Student doctor, please pause the tape and summarize what we’ve discussed about additional functions of the kidneys.

  • In addition to the maintenance of homeostasis, the kidneys have several other functions. Hormone production is one of them. The kidneys produce the enzyme renin which helps them regulate blood pressure. Another hormone produced by the kidneys is renal erythropoietic factor or REF which regulates the production of red blood cells in bone marrow. The kidneys also produce kinins and prostaglandins, both vasoactive substances. Activation of vitamin D3 is another function of the kidneys. Finally, when the body is in dire straits, the kidneys produce and secrete glucose from non-carbohydrate sources. Prolonged starvation and chronic respiratory acidosis are two conditions that would trigger this.

 

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