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- USMLE Audio Review files from our “Gold Standard USMLE Reviews”
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- Following along with the transcription
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Let’s start our USMLE Review with Anatomy from the Gold Standard USMLE Step 1 Audio Review program.
Play USMLE Audio MP3 58 09 Percent of Total Body Water Below
Begin 58 09 Percent of Total Body Water Transcription
Which fluid compartment comprises 33% of total body water?
- 33% of total body water is extracellular fluid.
Which compartment comprises about eight percent of total body water?
- The plasma.
Which compartment is about 25% of the total?
- Interstitial fluid comprises about 25% of total body water.
And what is about 67% of the total?
- Intracellular fluid.
What are ions that carry a positive electric charge called? The answer starts with a C.
- Cations are ions with a positive electric charge.
Which fluid compartment is potassium the major cation of?
- Potassium is the major cation of the intracellular fluid.
What is the major cation of all the other fluid compartments?
And what is the memory key for that?
- Potassium in, sodium out.
What are ions that carry a negative charge called?
What are the major anions of the interstitial fluid? They start with C and B.
- Chloride and bicarbonate are the major anions of interstitial fluid.
What are the three major anions of the plasma? I’ll cue you with the first letter of each.
and second, C.
and third, PP.
- Plasma protein.
What is the major anion of the extracellular fluid, including both the plasma and the interstitial fluid?
- Chloride is the major anion of the extracellular fluid.
What are the two major anions of the intracellular fluid?
- Protein and organic phosphates.
Student doctor, please pause the tape and summarize what we’ve discussed about the distribution of the total body water among the four main fluid compartments as well as the major cations and anions of each.
- 33% of total body water is extracellular fluid or ECF. About eight percent of total body water is plasma and about 25% is interstitial fluid. Intracellular fluid or ICF comprises about 67% of total body water. Cations are ions with a positive electric charge and anions are ions that carry a negative charge. Potassium is the major cation of the intracellular fluid. The major cation of all other fluid compartments is sodium. The memory key for this is potassium in, sodium out. Chloride and bicarbonate are the major anions of interstitial fluid and the three major anions of plasma are bicarbonate, chloride, and plasma protein. Chloride is the major anion of extracellular fluid including both the plasma and the interstitial fluid. The two major anions of the intercellular fluid are protein and organic phosphates.
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