USMLE Step 1 Renal Physiology Review 59 06 Various Osmolalities

USMLE Step 1 Renal Physiology Review 59 06 Various Osmolalities

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Play USMLE Audio MP3 59 06 Various Osmolalities Below

Begin  59 06 Various Osmolalities  Transcription

What is the osmolality of the fluid entering the renal tubule at Bowman’s capsule?

  • 280 to 300 milliosmoles/kg.

What is the approximate osmolality of the cortical interstitium?

  • Also about 280 to 300 milliosmoles.

Compare the osmolality of the fluid in the thin descending limb of the Loop of Henle at equilibrium to the osmolality of the surrounding interstitium.

At equilibrium, the osmolality of the fluid in the thin descending limb of Henle reflects the osmolality of the surrounding interstitium.

What is approximate osmolality of the fluid entering the thin descending limb?

  • About 280 to 300 milliosmoles.

In a juxtamedullary nephron, what is the osmolality of the tubular fluid as it makes the hairpin turn at the bottom of the Loop of Henle?

  • About 1200 milliosmoles.

What is the approximate osmolality of tubular fluid at the top of the thick ascending limb of Henle?

  • Probably somewhere between 100 and 200 milliosmoles.

Student doctor, please pause the tape and summarize what we’ve discussed about the osmolality of tubular fluid in the interstitium at various points.

The approximate osmolality of the fluid entering the renal tubule at Bowman’s capsule and of the cortical interstitium is 280 to 300 milliosmoles/kg. At equilibrium the osmolality of the fluid in the thin descending limb of Henle reflects the osmolality of the surrounding interstitium. The fluid entering the thin descending limb is about 280 to 300 milliosmoles. At the hairpin turn at the bottom of the Loop of Henle of a juxtamedullary nephron the osmolality of the fluid is about 1200 milliosmoles. At the top of the thick ascending limb of Henle, the osmolality of tubular fluid is probably somewhere between 100 and 200 milliosmoles/kg.

 

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