USMLE Step 1 Renal Physiology 1 Review 58 17 Maximum Tubular Transport Capacity

USMLE Step 1 Renal Physiology 1 Review 58 17 Maximum Tubular Transport Capacity

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Play USMLE Audio MP3 58 17 Maximum Tubular Transport Capacity Below

Begin 58 17 Maximum Tubular Transport Capacity Transcription

What is the general term for renal tubular reabsorption and secretion? It starts with TT.

  • Tubular transport.

What is the term for the highest attainable rate of reabsorption or secretion of a given solute or substance? It starts with MTTC.

  • The maximum tubular transport capacity is the highest attainable rate of reabsorption or secretion of a given substance or solute.

What is the symbol used to denote the maximum tubular transport capacity?

  • Tm. Many of the amino acids are examples of substances that are actively reabsorbed by the renal tubule cells and have a transport maximum.

List five other actively reabsorbed substances that have a transport maximum. I’ll cue you with the first letter or letters of each.

First, G.

  • Glucose.

Second, OM.

  • Other monosaccharides.

Third, KCI.

  • Kreb’s Cycle intermediates.

Fourth, PI.

  • Phosphate ions

and fifth, SI.

  • Sulfate ions.

What’s an example of a Kreb’s Cycle intermediate starting with AK?

  • Alpha-ketoglutarate.

Student doctor, please pause the tape briefly and repeat the actively reabsorbed substances that have a transport maximum.

  • Many amino acids, glucose, other monosaccharides, Kreb’s Cycle intermediates such as alpha-ketoglutarate, phosphate ions, and sulfate ions.

What is the term for the characteristic plasma concentration at which a reabsorbed substance begins to appear in the urine? It starts with TC.

  • The threshold concentration of a substance is the characteristic plasma concentration at which the substance begins to appear in the urine.

Student doctor, please pause the tape and summarize what we’ve discussed about the maximum tubular transport capacity, actively reabsorbed substances with a transport maximum, and threshold concentration.

  • The general term for renal tubular reabsorption and secretion is tubular transport. The maximum tubular transport capacity is the highest attainable rate of reabsorption or secretion of a given solute or substance. Many of the amino acids are examples of actively reabsorbed substances that have a transport maximum. Some other actively reabsorbed substances that have a reabsorptive Tm are glucose, other monosaccharides, Kreb’s Cycle intermediates such as alpha-ketoglutarate, phosphate ions, and sulfate ions. The threshold concentration of a substance is the characteristic plasma concentration at which the substance begins to appear in the urine.

****END OF TRANSCRIPTION****

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