USMLE Step 1 Renal Physiology 1 Review 58 19 Secreted Substances With a Tm

USMLE Step 1 Renal Physiology 1 Review 58 19 Secreted Substances With a Tm

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Play USMLE Audio MP3 58 19 Secreted Substances With a Tm Below

Begin 58 19 Secreted Substances With a Tm Transcription

Alphabetically, list seven secreted substances that have a transport maximum. I’ll cue you with the first letter of each.

First, C.

  • Creatinine.

Second, H.

  • Histamine.

Third, M.

  • Morphine.

Fourth, PAH.

  • Para-aminohippuric acid.

Fifth, P.

  • Penicillin.

Sixth, S.

  • Salicylate.

Seventh, T.

  • Thiamine.

Student doctor, please pause the tape briefly and repeat the secreted substances that have a transport maximum.

  • Creatinine, histamine, morphine, para-aminohippuric acid, penicillin, salicylate, thiamine.

What is an important function of the secretory transport systems?

  • The elimination of foreign chemicals from the body is an important function of the secretory transport systems.

The solute concentration gradient between what two renal fluids limits the transport rate of solutes that have no transport maximum?

  • If a solute has no transport maximum its transport rate is limited by the solute concentration gradient between the tubular fluid and the blood in the peritubular capillaries.

And what is this kind of transport process called?

  • A gradient-limited transport process.

What is one solute that is reabsorbed along the nephron yet has no transport maximum?

  • In other words, its transport rate is gradient-limited. Sodium.

Student doctor, please pause the tape and summarize what we’ve discussed about secreted substances with a transport maximum and gradient-limited transport processes.

  • Creatinine, histamine, morphine, para-aminohippuric acid, penicillin, salicylate, and thiamine are all secreted substances that have a transport maximum. The elimination of foreign chemicals from the body is an important function of the secretory transport systems. If a solute has no transport maximum, its transport rate is limited by the solute concentration gradient between the tubular fluid and the blood in the peritubular capillaries. This is a gradient-limited transport process. The transport of sodium which is reabsorbed along the nephron, yet has no transport maximum, is gradient-limited.

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