USMLE Step 1 Respiratory Physiology Review 60 16 Terms of oxygen Transport 2

USMLE Step 1 Respiratory Physiology Review 60 16 Terms of oxygen Transport 2

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Begin 60 16 Terms of oxygen Transport 2 Transcription

What is the term for the maximum amount of oxygen that can be carried by the hemoglobin? The answer starts with OC.

  • Oxygen capacity is the maximum amount of oxygen that can be carried by the hemoglobin.

How many grams of hemoglobin does the blood of an adult male typically contain per deciliter?

  • 15 grams of hemoglobin per deciliter.

What is the amount of oxygen that can combine with each gram of hemoglobin? Give your answer in milliliters.
So hemoglobin has the capacity to carry how much oxygen in one deciliter of blood. Give your answer in milliliters per deciliter.

  •  Hemoglobin has the capacity to carry 20.1 to 20.9 milliliters oxygen per deciliter blood.    

What is the term for the percent of hemoglobin that is combined with oxygen? The two word answer starts with HS.

  • Hemoglobin saturation.

Remember that each hemoglobin molecule can combine with as many as four molecules of oxygen.
If a hemoglobin molecule is said to be 100 percent saturated with oxygen, what does this mean?

  •  A hemoglobin molecule is said to be 100 percent saturated with oxygen when all four sites on the molecule are occupied by oxygen.

What is the normal hemoglobin saturation of arterial blood?

  • Normally, arterial hemoglobin saturation is about 98%.

What is the typical value for hemoglobin saturation of venous blood?

  • Typical hemoglobin saturation of venous blood is about 70%.

Student doctor please pause the tape and summarize what has been discussed about oxygen capacity and hemoglobin saturation.

  •  Oxygen capacity is the maximum amount of oxygen in blood that can be carried by the hemoglobin. The blood of an adult male typically contains 15 grams of hemoglobin per deciliter. The amount of oxygen that can combine with each gram of hemoglobin is from 1.34 to 1.39 milliliters. Hemoglobin has the capacity to carry 20.1 to 20.9 milliliters oxygen per deciliter blood. Hemoglobin saturation is the term for the percent of hemoglobin that is combined with oxygen. Since each hemoglobin molecule can combine with as many as four molecules of oxygen, if a hemoglobin molecule is said to be 100% saturated with oxygen, this means that all four sites on the molecule are occupied by oxygen. Normally, arterial hemoglobin saturation is about 98%. Typical hemoglobin saturation of venous blood is about 70%.

What is the term for the total amount of oxygen in blood? The two word answer starts with OC.

  • Oxygen content is the total amount of oxygen in blood.

What two things added together equal oxygen content?

  • The amount of oxygen bound to hemoglobin and the amount of dissolved oxygen.

Approximately, how many milliliters of oxygen per deciliter blood does arterial blood carry? In other words, what is the oxygen content of arterial blood in milliliters per deciliter?

  •  The oxygen content of arterial blood is about 20 milliliters of oxygen per deciliter blood.

What does the expression, ‘the affinity of hemoglobin for oxygen’, mean?

  •    It is the ease with which hemoglobin combines with oxygen.

What organic phosphate regulates hemoglobin’s affinity for oxygen?

  •    2,3 Diphosphoglycerate, or 2,3 DPG, regulates hemoglobin’s affinity for oxygen.

How do 2-3 DPG and hemoglobin interact?

  • 2,3 DPG binds to the beta chains in hemoglobin.

What effect does an increase in 2,3 DPG have on hemoglobin’s oxygen affinity?

  •  An increase in 2,3 DPG decreases hemoglobin’s oxygen affinity.

Student doctor, please pause the tape and summarize what we have discussed about oxygen content, the affinity of hemoglobin for oxygen, and 2,3 DPG.

  • Oxygen content is the total amount of oxygen in blood. The amount of oxygen bound to hemoglobin and the amount of dissolved oxygen added together equal oxygen content. The oxygen content of arterial blood is about 20 milliliters of oxygen per deciliter blood. The affinity of hemoglobin for oxygen is the ease with which hemoglobin combines with oxygen. The organic phosphate, 2,3 Diphosphoglycerate, or 2,3 DPG, regulates hemoglobin’s affinity for oxygen. 2,3 Diphosphoglycerate binds to the beta chains in hemoglobin. An increase in 2,3 DPG decreases hemoglobin’s oxygen affinity.

 

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