USMLE Step 1 Respiratory Physiology Review 61 03 Acid Base Disorders 1_3

USMLE Step 1 Respiratory Physiology Review 61 03 Acid Base Disorders 1_3

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Play USMLE Audio MP3  61 03 Acid Base Disorders 1_3  Below

Begin  61 03 Acid Base Disorders 1_3  Transcription

Now let’s talk about acid base disorders. The four acid base disorders we’re going to look at here are all uncompensated. I’ll give the primary disturbance, please respond with the disorder.

First, increased partial pressure of carbon dioxide

  • respiratory acidosis

Second, decreased PCO2

  • Respiratory alkalosis

Third, Increased hydrogen ion concentration-

  • metabolic acidosis

And fourth, decreased hydrogen ion concentration

  • metabolic alkalosis

For each of the following disorders, describe what happens to the pH, the hydrogen ion concentration, the PCO2, and the bicarbonate.

Respiratory acidosis.

  • With respiratory acidosis, the pH goes below 7.35, hydrogen ion concentration rises, PCO2 rises, and bicarbonate rises.

Respiratory Alkalosis

  • With respiratory alkalosis, the pH goes above 7.45, hydrogen ion concentration drops, PCO2 drops, and bicarbonate drops.

Metabolic acidosis.

  • With metabolic acidosis, the pH goes below 7.35, hydrogen ion concentration rises, PCO2 drops, and bicarbonate drops as well.

And finally, metabolic alkalosis.

  • With metabolic alkalosis, the pH goes above 7.45, hydrogen ion concentration drops, PCO2 rises, and bicarbonate rises as well. 

Student doctor, please pause the tape and summarize what we’ve discussed about respiratory and metabolic acidosis and alkalosis.

  • The primary disturbance of uncompensated respiratory acidosis is increased PCO2. For respiratory alkalosis, it is decreased PCO2. For metabolic acidosis, it is increased hydrogen ion concentration. And for metabolic alkalosis, it is decreased hydrogen ion concentration. With respiratory acidosis, the pH goes below 7.35, hydrogen ion concentration rises, PCO2 rises, and bicarbonate rises. With respiratory alkalosis, the pH goes above 7.45, hydrogen ion concentration drops, PCO2 drops, and bicarbonate drops. With metabolic acidosis, the pH goes below 7.35, the hydrogen ion concentration rises, PCO2 drops, and bicarbonate drops. With metabolic alkalosis, the pH goes above 7.45, the hydrogen ion concentration drops, PCO2 rises, and bicarbonate rises as well.

 

 

****END OF TRANSCRIPTION****

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