On these “Gold Standard Step 1 Facts” pages you will find Free:
- USMLE Audio Review files from our “Gold Standard USMLE Reviews”
- Transcriptions of those files
- And videos (as they become available)
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- Listening to the Audio
- Following along with the transcription
- Or by watching the video (if available)
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Let’s start our USMLE Review with Anatomy from the Gold Standard USMLE Step 1 Audio Review program.
Play USMLE Audio MP3 62 04 Lung Products Below
Begin 62 04 Lung Products Transcription
Now let’s talk about lung products.
What is the lung product that reduces surface tension in the alveoli? It starts with an S.
Surfactant is mostly what compound? The three word answer starts with DPC?
- Surfactant is mostly dipalmitoyl-phosphatidyl-choline
What compound in the lungs converts angiotensin 1 to angiotensin 2 and inactivates bradykinin? It’s acronym is ACE
- Angiotensin converting enzyme.
And which compound activates bradykinin, which dilates arterials and constricts veins and also increases filtration out of capillaries?
Which acts similarly bradykinin including causing local edema by increasing filtration out of capillaries? It starts with an H.
- Histamine acts similarity to bradykinin
And finally, what are the various vasodilators and vasoconstrictors called? The answer starts with a P
- The prostaglandins
Alright, here is a quick review of the lung products just discussed and then we will be finished with respiratory physiology
What compound is surfactant?
And what two actions does angiotensin converting enzyme, ACE, perform?
- Angiotensin converting enzyme converts angiotensin 1 to angiotensin 2 and inactivates bradykinin
What action does Kallikrein have?
- Kallikrein activates bradykinin
And what does bradykinin do?
- Bradykinin dilates arterially, constricts veins, and increases filtration out of the capillaries
What does histamine do?
- Histamine acts similar to bradykinin including causing local edema
And what do prostaglandins do?
- These are local products that are various vasodilators and vasoconstrictors.
Student doctor, please pause the tape and summarize what we’ve discussed about lung products.
The lung product that reduces surface tension in the alveoli is surfactant, which is mostly dipalmitoyl-phosphatidyl-choline. Angiotensin converting enzyme, ACE, converts angiotensin 1 to angiotensin 2, and inactivates bradykinin. Kallikrein activates bradykinin. Bradykinin dilates arteriole, constricts veins, and increases filtration out of the capillaries. Histamine acts similarly to bradykinin including causing local edema. And finally, the prostaglandins are local products that are various vasodilators and vasoconstrictors.
****END OF TRANSCRIPTION****
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