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Let’s start our USMLE Review with Drugs of Choice from the Gold Standard USMLE Step 2 Audio Review program.
Play USMLE Audio MP3 18 11 Drugs of Choice Neonatal Pneumonia Below
Begin 18 11 Drugs of Choice Neonatal Pneumonia Transcription
- E. coli.
What group of organisms are next most likely?
- Group A, B, or G Strep.
What 2 antibiotics are administered together as the drug of choice for severe pneumonia in a neonate (birth to 5 days)?
- Ampicillin and Gentamycin.
And what are the trade names for Ampicillin?
- Ampicillin is in Omnipen, Principen, or Unasyn.
And the trade name for Gentamycin?
Again, what are the 2 drugs of choice administered together for neonatal pneumonia (birth to 5 days)?
- Ampicillin and Gentamycin.
And the trade names for both?
- Ampicillin is Omnipen, Princepen or Unasyn; Gentamycin is Garamycin.
What is the drug of choice for torsades de pointes?
- Magnesium sulfate.
Is magnesium sulfate still the drug of choice for torsades de pointes if serum magensium levels are normal?
What is the drug of choice for compulsive hair pulling?
- It is also the drug of choice for obsessive compulsive disorders, and also used for depression. Clomipramine.
And the trade name for Clomiprimine?
And what class of drug is Clomiprimine/Anafranil?
- It’s a tricyclic.
What is the drug of choice for genital herpes simplex (primary or recurrent) in both the immunocompetent and immunocompromised patient?
And the trade name for Acyclovir?
What is the drug of choice for both acute and chronic copper poisoning?
And what are 2 trade names for D-penicillimine?
- Cuprimine and Depen.
What is the drug of choice for all tapeworms in humans- mainly those that have come from eating uncooked beef, pork, or fish, or swallowing eggs of the dog or dwarf tapeworms?
Again, generic and trade name for tapeworms?
What is the vitamin pro-coagulant, sometimes needed in premature infants?
- Vitamin K.
And what is another name for vitamin K3?
What is the first line drug of choice for acute attacks of migraine or acute cluster headache?
What type of drug is Sumatriptan?
- A serotonin agonist.
Specifically, what receptor is stimulated by Sumatriptan?
And the trade name for Sumatriptan?
How is Sumatriptan/Imitrex administered?
- PO or subcutaneous injection.
If Sumatriptan/Imitrex doesn’t work, what combination is the next choice (this used to be the first line treatment)?
- Ergotamine Tartrate and Caffeine.
And the mechanism of action of Ergotamine and Caffeine?
- Either PO or rectal suppository.
Now the trade name for Ergotamine Tarartrate and caffeine in a rectal suppository form?
Trade name for Ergotamine Tartrate and Caffeine in PO Tab form?
Ergotamine Tartrate is also available by itself in IM or IV injection form, when other means of administration are not available. Trade name?
What is an effective prophylactic Ergot alkaloid drug for migraine, which can only be administered for 3 months at a time, with a rest in between?
And the trade name for Methysergide?
What is the side effect which limits use to only 3 months at a time for Methysergide/Sansert?
- Retroperitoneal fibrosis.
What 2 drugs offer long term prophylaxis in about 50% of patients but should not be used with patients that have bradycardia, heart block, CHF, or asthma?
- Propranolol or Timolol.
What class of drugs are Propranolol or Timolol?
- They’re both non-cardioselective beta blockers.
And the trade name for Propranolol?
And the trade name for Timolol?
For chronic headache, which is psychogenic or post-traumatic and does not migraine or cluster, physicians sometimes supplement Aspirin or Acetominophen with what 2 classes of drugs, despite their potential for abuse and side effects?
- Tricyclics or Benzodiazepines.
What is the usual organism in a rat bite?
- Streptobacillus moniliformis.
And the drug of choice?
- Amoxicillin plus Clavulanate.
And the trade name?
What is a good alternative if the patient is allergic to Penicillins?
Is rabies prophylaxis usually indicated in a rat bite?
- Surprisingly, no.
What is the NSAID of choice for menstrual cramps?
- It’s also used for arthritis, bursitis, tendonitis.
And what are 3 trade names for Ibuprofen?
- Advil, Motrin, Nuprin.
What are the 2 most likely organisms in a brain abscess in an AIDS patient?
- Toxoplasma or Nocardia.
What is the combination drug of choice for ongoing infection with toxoplasmosis?
- Pyrimethamine Sulfadiazine.
And the trade name?
While treatment of Nocardia brain abscess in AIDS is complicated and difficult, which is the drug of choice for starting a multi-drug regimen?
- Trimethoprim Sulfa.
And what are 2 trade names for Trimethoprim Sulfa?
- Bactrim, Septra.
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